A novel automatic suspicious mass regions identification using Havrda & Charvat entropy and Otsu's N thresholding

Mass detection is a very important process for breast cancer diagnosis and computer aided systems. It can be very complex when the mass is small or invisible because of dense breast tissue. Therefore, the extraction of suspicious mass region can be very challenging. This paper proposes a novel segmentation algorithm to identify mass candidate regions in mammograms. The proposed system includes three parts: breast region and pectoral muscle segmentation, image enhancement and suspicious mass regions identification. The first two parts have been examined in previous studies. In this study, we focused on suspicious mass regions identification using a combination of Havrda & Charvat entropy method and Otsu's N thresholding method. An open access Mammographic Image Analysis Society (MIAS) database, which contains 59 masses, was used for the study. The proposed system obtained a 93% sensitivity rate for suspicious mass regions identification in 56 abnormal and 40 normal images.     

Multiple metastatic infections in a hemodialysis patient with untunneled internal jugular catheter

We present an end‐stage renal disease patient on dialysis with fever. The primary source was right internal jugular vein catheter which had metastatic infections in the body probably via an arteriovenous communication in a cavity in left lung. Patient had right psoas muscle abscess and a left kidney abscess. An ¹⁸F‐fluorodeoxyglucose‐positron emission spectroscopy scan was done to find out left kidney abscess. A search of literature did not reveal many patients of psoas abscess secondary to infection of hemodialysis access.     

Serine Protease Inhibitors as Good Predictors of Meat Tenderness: Which Are They and What Are Their Functions?

Since years, serine proteases and their inhibitors were an enigma to meat scientists. They were indeed considered to be extracellular and to play no role in postmortem muscle proteolysis. In the 1990's, we observed that protease inhibitors levels in muscles are a better predictor of meat tenderness than their target enzymes. From a practical point of view, we therefore choose to look for serine protease inhibitors rather than their target enzymes, i.e. serine proteases and the purpose of this report was to overview the findings obtained. Fractionation of a muscle crude extract by gel filtration revealed three major trypsin inhibitory fractions designed as F1 (Mr:50–70 kDa), F2 (Mr:40–60 kDa) and F3 (Mr:10–15kD) which were analyzed separately. Besides antithrombin III, an heparin dependent thrombin inhibitor, F1 and F2 comprised a large set of closely related trypsin inhibitors encoded by at least 8 genes bovSERPINA3-1 to A3-8 and able to inhibit also strongly initiator and effector caspases. They all belong to the serpin superfamily, known to form covalent complexes with their target enzymes, were located within muscle cells and found in all tissues and fluids examined irrespective of the animal species. Potential biological functions in living and postmortem muscle were proposed for all of them. In contrast to F1 and F2 which have been more extensively investigated only preliminary findings were provided for F3. Taken together, these results tend to ascertain the onset of apoptosis in postmortem muscle. However, the exact mechanisms driving the cell towards apoptosis and how apoptosis, an energy dependent process, can be completed postmortem remain still unclear.     

Control of a robotic orthosis for gait rehabilitation

Robot assisted gait training may help in producing rapid improvements in functional gait parameters. This paper presents new experimental results with an intrinsically compliant robotic gait training orthosis. The newly developed robotic orthosis has 6 degrees of freedom (DOFs). A trajectory tracking controller based on the boundary layer augmented sliding control (BASMC) law was implemented to guide the subject’s limbs on physiological gait trajectories. The compliance of the robotic orthosis sagittal plane hip and knee joints was also controlled, independently of the trajectory tracking control. The robotic orthosis and the control scheme were evaluated on three neurologically intact subjects walking on a treadmill. A maximum trajectory tracking error of 10° was recorded at the hip and knee sagittal plane joints. The results showed that subjects can walk in the robotic orthosis with comfort and the BASMC law was able to guide the subject’s limbs on reference physiological trajectories.     

预处理温度对SAPO-11催化丁烯骨架异构化性能的影响

采用水热合成法合成的SAPO-11分子筛，经酸洗、干燥和焙烧处理得H-SAPO-11分子筛，考察了预处理温度对催化剂物化性能的影响，采用XRD、XRF、IR和NH₃-TPD等手段对催化剂进行表征。实验证明，500 ℃预处理后H-SAPO-11分子筛的结构缺陷较少，B酸位较多，骨架更完美；将其成型制成催化剂，对丁烯骨架异构化反应显示更优良的催化活性、选择性和稳定性。     

Wireless Face Interface: Using voluntary gaze direction and facial muscle activations for human-computer interaction

The present aim was to investigate the functionality of a new wireless prototype called Face Interface. The prototype combines the use of voluntary gaze direction and facial muscle activations, for pointing and selecting objects on a computer screen, respectively. The subjective and objective functionality of the prototype was evaluated with a series of pointing tasks using either frowning (i.e., frowning technique) or raising the eyebrows (i.e., raising technique) as the selection technique. Pointing task times and accuracies were measured using three target diameters (i.e., 25, 30, 40 mm), seven pointing distances (i.e., 60, 120, 180, 240, 260, 450, and 520 mm), and eight pointing angles (0°, 45°, 90°, 135°, 180°, 225°, 270°, and 315°). The results showed that the raising technique was faster selection technique than the frowning technique for the objects that were presented in the pointing distances from 60 mm to 260 mm. For those pointing distances the overall pointing task times were 2.4 s for the frowning technique, and 1.6 s for the raising technique. Fitts’ law computations showed that the correlations for the Fitts’ law model were r = 0.77 for the frowning technique and r = 0.51 for the raising technique. Further, the index of performance (IP) value was 1.9 bits/s for the frowning technique and 5.4 bits/s for raising the eyebrows technique. Based on the results, the prototype functioned well and was adjustable so that two different facial activations can be used in combination with gaze direction for pointing and selecting objects on a computer screen.     

Optimisation of rancidity stability in long‐chain PUFA concentrates obtained from a rainbow trout (Oncorhynchus mykiss) by‐product

This research was focused on the production of polyunsaturated fatty acid concentrates from a farmed rainbow trout (Oncorhynchus mykiss) by‐product (i.e. belly muscle). The effect of different process variables (urea/fatty acids (FA) contents ratio, crystallisation time and temperature and stirring speed of the urea/FA mixture) on the lipid oxidation development during the urea complexation process was investigated. For this purpose, an experimental design (26 runs) following the response‐surface methodology was developed. As a result, peroxide value and TOTOX index showed to be dependent on the crystallisation time and temperature and the urea/FA ratio, while no influence of the crystallisation stirring speed was detected on both indices; additionally, polyene index was affected by the urea/FA ratio and its interaction with the crystallisation time. An optimised desirability score near 1.0 was attained provided values of 2.8 °C, 3.05 h and 3.57 were applied for crystallisation temperature, crystallisation time and urea/FA ratio, respectively.     

Curved muscles in biomechanical models of the spine: a systematic literature review

Abstract

Early biomechanical spine models represented the trunk muscles as straight-line approximations. Later models have endeavoured to accurately represent muscle curvature around the torso. However, only a few studies have systematically examined various techniques and the logic underlying curved muscle models. The objective of this review was to systematically categorise curved muscle representation techniques and compare the underlying logic in biomechanical models of the spine. Thirty-five studies met our selection criteria. The most common technique of curved muscle path was the ‘via-point’ method. Curved muscle geometry was commonly developed from MRI/CT database and cadaveric dissections, and optimisation/inverse dynamics models were typically used to estimate muscle forces. Several models have attempted to validate their results by comparing their approach with previous studies, but it could not validate of specific tasks. For future needs, personalised muscle geometry, and person- or task-specific validation of curved muscle models would be necessary to improve model fidelity.

Practitioner Summary: The logic underlying the curved muscle representations in spine models is still poorly understood. This literature review systematically categorised different approaches and evaluated their underlying logic. The findings could direct future development of curved muscle models to have a better understanding of the biomechanical causal pathways of spine disorders.     

Work-related chronic injuries of the forearm and hand: their specific diagnosis and management

Work-related chronic injuries occur in muscles, tendons, and nerves. Epidemiological, histological, and physiological data confirm their often disputed physical basis. Terms such as repetitive strain injury and cumulative trauma disorder, when used as a diagnosis, have obscured the issue for they are really statements of causation. Definitive diagnosis is required both to treat and prevent such injuries. Precise terminology that identifies the tissue and its pathology is required. A detailed assessment methodology is described that allows a precise diagnosis. A clear relationship to work stress is necessary both to establish the cause and formulate prevention strategies. Treatment must begin early and be appropriate to the tissue and the nature of the injury. Examples are presented and discussed. Early treatment begins before too much damage has been done and yields better results.     

Antioxidant mechanism of grape procyanidins in muscle tissues: Redox interactions with endogenous ascorbic acid and α-tocopherol

The present study investigates the antioxidant mechanism of grape procyanidins and, in particular, their aptitude to establish redox interactions with two important components of the endogenous antioxidant system of muscle tissues, α-tocopherol (α-TOH) and ascorbic acid (AA). To this end, the progress of lipid oxidation was monitored in fish muscle supplemented with grape procyanidins at the concentrations usually employed in antioxidant food applications, and then related to the redox stability of the endogenous α-TOH and AA. In addition to the lipid oxidation protective effect, the incorporation of procyanidins also provided an improvement of the redox stability of the endogenous components in a straight procyanidinic concentration-dependent manner. Results showed the capacity of procyanidins to repair oxidised α-TOH at medium-long term, and to delay the AA depletion. Therefore, such cooperative redox interaction of exogenous procyanidins adequately complements the natural α-TOH regenerative system supplied by AA that is efficient at the early post mortem stages.